System suitability in UV Methods
What criteria can be defined for system suitability in UV Methods for Assay, Impurities (Limit test)
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Pharmacopeia do not define specific system suitability tests for UV methods. However the following may be considered.
- A test of repeatability by measurement of response of a standard solution, for example response of standard in five replicates (with %RSD to be less than 2.0%)
- Resolution with a solution of toluene in hexane, criteria – ratio between the minimum and maximum absorbance at respective wavelengths of 267 and 269 nm must exceed 1.3 (USP).
Useful references:
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Pharmacopeia do not define specific system suitability tests for UV methods. However the following may be considered.
Useful references: